Zu Ylem Dust

Zu Ylem Dust is used by the Gargoyles to knock out even a large animal with just a single pouch. It appears in  Ultima VI.

Description
It was used most often by hunters, to avoid harming the meat. Unfortunately, the powder was made from plants that could no longer be found, as they were destroyed in the great cataclysms that ultimately destroyed the Gargish lands.

Trivia

 * Sleeping powder does exist in Ultima VII, makign one wonder if mankind managed to copy the Zu Ylem Dust.