Ophidians (Ultima Online)

Ophidians are snake-like, swamp-dwelling creature that populate The Lost Lands and first appeared in Ultima Online: The Second Age and look like some sort of hybrid between man and snake. They are sworn enemies to the Terathans.

In Ultima X
Ophidians meant were to be included in the cancelled Ultima X. See Ultima X Ophidian for details. 

Trivia

 * While it does appears these creatures have any relation to the Ophidians of the Serpent Isle, they appear to be similar to the Naga that can be found there.