Daemon Bones

Daemon Bones (DB) are a reagent that is in use on Pagan. As the name already says, these are the bones of daemons, which makes acquisition of this reagent downright dangerous.

Pagan
The school of Sorcery found out, that even after death, the bones of a daemon retain the powers found in them during life. In a perverse twist this resulted in them being essential in spells for elements of summoning and binding, primarily of other daemons. Since a daemon had to be slain to gain these bones -a task very lethal as the daemon won't part with them peacefully- it was the most difficult reagent to acquire for a Sorcerer.

Ultima Online
When the Stygian Abyss expansion opened, it was found that the gargoyle Mysticism school of magic makes use of daemon bones as a reagent.

Trivia

 * Adding demon bones to any spell where they are not required does have bad consequences. A daemon appears to kill the sorcerer for using the bones of its kin. This also results in the destruction of the candles, reagents and focus.